• To enhance the chin for a more defined profile.
• These non-surgical packages are designed to improve facial symmetry, provide a more sculpted look.

What is Restylane® Defyne for?
As you age, your facial skin begins to lose its elasticity and volume. As a result, your “laugh lines”, the creases that run from the sides of your nose toward the corners of your mouth, become more pronounced.

Restylane® Defyne injectable gel is designed to temporarily help counter this by smoothing out these wrinkles and folds and restoring a natural, soft look to your face.

Restylane® Defyne may also be used for augmentation of the chin region to improve the chin profile in patients with mild to moderate chin retrusion over the age of 21. This means it may be used in the chin area to improve the profile, shape, and size of your chin.

Restylane® Defyne has been shown to maintain this effect for up to 12 months.

Are there any reasons why I should not receive Restylane® Defyne?
Before using Restylane® Defyne, your doctor will talk to you about your medical history, to determine if you are an appropriate candidate for treatment. You will be asked questions about possible allergies to ensure that Restylane® Defyne can be safely administered. Tell your doctor about all your medical conditions, including if you:
• Have severe allergies with a history of severe reactions (anaphylaxis). Use of Restylane® Defyne may result in an allergic reaction.
• Are allergic to the anesthetic lidocaine or to any of the proteins used to make the hyaluronic acid in Restylane® Defyne (bacterial proteins). Use may result in an allergic reaction.

What side effects were seen in the clinical studies?
In the study of Restylane® Defyne for correction of wrinkles and folds that form around your nose and extend down to the corners of your mouth (laugh lines), most patients reported the following side effects at the site where they received the injection:
• Swelling
• Lumps/Bump Formation
• Redness
• Pain/Tenderness
• Bruising
• Itching
Most patients said their side effects were mild, short-lived, and did not require them to call their doctor.
These patients said that their side effects disappeared within 1-2 weeks.
Patients also reported that the anesthetic lidocaine, which is part of the Restylane® Defyne injection and used to numb the injection site, significantly reduced pain during and after their procedure.